Only a small fraction of cells produce assembled capsids during transfection‐based manufacturing of adeno‐associated virus vectors

Plasmid transfection of mammalian cells is the dominant platform used to produce adeno‐associated virus (AAV) vectors for clinical and research applications. Low yields from this platform currently make it difficult to supply these activities with adequate material. In an effort to better understand...

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Detalles Bibliográficos
Autores principales: Dash, Shantoshini, Sharon, David M., Mullick, Alaka, Kamen, Amine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
COMMUNICATION
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314941/
https://www.ncbi.nlm.nih.gov/pubmed/35182435
http://dx.doi.org/10.1002/bit.28068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314941/
https://www.ncbi.nlm.nih.gov/pubmed/35182435
http://dx.doi.org/10.1002/bit.28068

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