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Only a small fraction of cells produce assembled capsids during transfection‐based manufacturing of adeno‐associated virus vectors
Plasmid transfection of mammalian cells is the dominant platform used to produce adeno‐associated virus (AAV) vectors for clinical and research applications. Low yields from this platform currently make it difficult to supply these activities with adequate material. In an effort to better understand...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314941/ https://www.ncbi.nlm.nih.gov/pubmed/35182435 http://dx.doi.org/10.1002/bit.28068 |