Late‐Stage Chemoenzymatic Installation of Hydroxy‐Bearing Allyl Moiety on the Indole Ring of Tryptophan‐Containing Peptides

The late‐stage functionalization of indole‐ and tryptophan‐containing compounds with reactive moieties facilitates downstream diversification and leads to changes in their biological properties. Here, the synthesis of two hydroxy‐bearing allyl pyrophosphates is described. A chemoenzymatic method is...

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Detalles Bibliográficos
Autores principales: Mupparapu, Nagaraju, Brewster, Lauren, Ostrom, Katrina F., Elshahawi, Sherif I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314954/
https://www.ncbi.nlm.nih.gov/pubmed/35178791
http://dx.doi.org/10.1002/chem.202104614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314954/
https://www.ncbi.nlm.nih.gov/pubmed/35178791
http://dx.doi.org/10.1002/chem.202104614

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