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Regulation of coagulation by tissue factor pathway inhibitor: Implications for hemophilia therapy

Tissue factor pathway inhibitor (TFPI) is an alternatively spliced anticoagulant protein that primarily dampens the initiation phase of coagulation before thrombin is generated. As such, TFPI’s actions are localized to cells expressing TF and to sites of injury, where it is an important regulator of...

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Detalles Bibliográficos
Autores principales: Mast, Alan E., Ruf, Wolfram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314982/
https://www.ncbi.nlm.nih.gov/pubmed/35279938
http://dx.doi.org/10.1111/jth.15697