The two pore potassium channel THIK‐1 regulates NLRP3 inflammasome activation

The NLRP3 (NLR family, pyrin domain containing 3) inflammasome is a multi‐protein complex responsible for the activation of caspase‐1 and the subsequent cleavage and activation of the potent proinflammatory cytokines IL‐1β and IL‐18, and pyroptotic cell death. NLRP3 is implicated as a driver of infl...

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Detalles Bibliográficos
Autores principales: Drinkall, Samuel, Lawrence, Catherine B., Ossola, Bernadino, Russell, Samuel, Bender, Clare, Brice, Nicola B., Dawson, Lee A., Harte, Michael, Brough, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314991/
https://www.ncbi.nlm.nih.gov/pubmed/35353387
http://dx.doi.org/10.1002/glia.24174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314991/
https://www.ncbi.nlm.nih.gov/pubmed/35353387
http://dx.doi.org/10.1002/glia.24174

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