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Reductant‐Free Cross‐Electrophile Synthesis of Di(hetero)arylmethanes by Palladium‐Catalyzed Desulfinative C−C Coupling

An efficient Pd‐catalyzed one‐pot desulfinative cross‐coupling to access medicinally relevant di(hetero)arylmethanes is reported. The method is reductant‐free, and involves a sulfinate transfer reagent and a Pd‐catalyst mediating the union of two electrophilic coupling partners; a (hetero)aryl halid...

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Detalles Bibliográficos
Autores principales: McKnight, Janette, Shavnya, Andre, Sach, Neal W., Blakemore, David C., Moses, Ian B., Willis, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314995/
https://www.ncbi.nlm.nih.gov/pubmed/35229419
http://dx.doi.org/10.1002/anie.202116775