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A Secretory Vesicle Failure in Parkinson's Disease Occurs in Human Platelets

OBJECTIVE: The presence of elevated dopamine (DA) and its major metabolites in the cytosol of neurons has been associated with their vulnerability in Parkinson's disease (PD). Over 99% of the cell's amines are confined to secretory vesicles (SVs), making these structures fundamental in the...

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Detalles Bibliográficos
Autores principales: Montenegro, Pablo, Pueyo, Mercedes, Lorenzo, Jesús Norelis, Villar‐Martinez, María Dolores, Alayón, Antonio, Carrillo, Francisco, Borges, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315021/
https://www.ncbi.nlm.nih.gov/pubmed/35226382
http://dx.doi.org/10.1002/ana.26335