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Phosphoproteomics identifies pathways underlying the role of receptor‐interaction protein kinase 3 in alcohol‐associated liver disease and uncovers apoptosis signal‐regulating kinase 1 as a target

Receptor‐interaction protein kinase 3 (RIP3), a critical determinant of the necroptotic pathway of programmed cell death, contributes to injury in murine models of alcohol‐associated liver disease (ALD); however, the underlying mechanisms are unknown. We investigated the effect of chronic ethanol fe...

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Detalles Bibliográficos
Autores principales: Singh, Vaibhav, Huang, Emily, Pathak, Vai, Willard, Belinda B., Allende, Daniela S., Nagy, Laura E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315126/
https://www.ncbi.nlm.nih.gov/pubmed/35438255
http://dx.doi.org/10.1002/hep4.1956