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Gut Commensal Fungi Protect Against Acetaminophen-Induced Hepatotoxicity by Reducing Cyp2a5 Expression in Mice

BACKGROUND AND AIMS: Drug-induced liver injury (DILI) is a common cause of acute liver failure and represents a significant global public health problem. When discussing the gut-liver axis, although a great deal of research has focused on the role of gut microbiota in regulating the progression of D...

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Detalles Bibliográficos
Autores principales: He, Zhuoen, Zeng, Yunong, Li, Shuyu, Lin, Lizhen, Zhou, Ruisi, Wang, Fangzhao, Yang, Wenjiao, Wu, Yuhao, Yang, Junhao, Chen, Ali, Wang, Zhang, Yang, Hong, Zhao, Xiaoshan, Xiao, Wei, Li, Lei, Gong, Shenhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315200/
https://www.ncbi.nlm.nih.gov/pubmed/35903481
http://dx.doi.org/10.3389/fmicb.2022.944416