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Theaflavin-3,3′-Digallate from Black Tea Inhibits Neointima Formation Through Suppression of the PDGFRβ Pathway in Vascular Smooth Muscle Cells

The abnormal neointima formation caused by the phenotypic switching of vascular smooth cells (VSMCs) into a synthetic state plays a key role in the pathogenesis of various vascular diseases, including atherosclerosis and postangioplasty restenosis. Theaflavin-3,3′-digallate (TF3) in black tea has be...

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Detalles Bibliográficos
Autores principales: Wu, Yichen, Chen, Min, Chen, Zilong, Shu, Jiangcheng, Zhang, Luoying, Hu, Jiong, Yu, Hongjun, Huang, Kai, Liang, Minglu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315285/
https://www.ncbi.nlm.nih.gov/pubmed/35903325
http://dx.doi.org/10.3389/fphar.2022.861319