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Imputation of Ancient Whole Genome Sus scrofa DNA Introduces Biases Toward Main Population Components in the Reference Panel

Sequencing ancient DNA to high coverage is often limited by sample quality and cost. Imputing missing genotypes can potentially increase information content and quality of ancient data, but requires different computational approaches than modern DNA imputation. Ancient imputation beyond humans has n...

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Detalles Bibliográficos
Autores principales: Erven, J. A. M., Çakirlar, C., Bradley, D. G., Raemaekers, D. C. M., Madsen, O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315352/
https://www.ncbi.nlm.nih.gov/pubmed/35903348
http://dx.doi.org/10.3389/fgene.2022.872486