An assessment of genome-editing efficiency of a newly developed Cas9 in C. elegans

Minimizing the off-target effects of the programmable genome editing tool CRISPR/Cas9 is critical for its potential therapeutic applications. A recent study reported a new Cas9 variant, SuperFi-Cas9, that dramatically reduces off-target DNA cleavage while retaining on-target DNA cleavage activity in...

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Detalles Bibliográficos
Autores principales: Ferdousy, Sakia, Chen, Bojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2022
Materias:
Negative Result
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315413/
https://www.ncbi.nlm.nih.gov/pubmed/35903778
http://dx.doi.org/10.17912/micropub.biology.000601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315413/
https://www.ncbi.nlm.nih.gov/pubmed/35903778
http://dx.doi.org/10.17912/micropub.biology.000601

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