Physiology-Based Pharmacokinetic Study on 18β-Glycyrrhetic Acid Mono-Glucuronide (GAMG) Prior to Glycyrrhizin in Rats

To understand that 18β-Glycyrrhetic acid 3-O-mono-β-D-glucuronide (GAMG) showed better pharmacological activity and drug-like properties than 18β-Glycyrrhizin (GL); a rapid and sensitive HPLC-MS/MS method was established for the simultaneous determination of GAMG and its metabolite 18β-Glycyrrhetini...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Mengxin, Zuo, Jiawei, Yang, Jian-Guo, Wu, Chenyao, Yang, Yongan, Tang, Wenjian, Zhu, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315563/
https://www.ncbi.nlm.nih.gov/pubmed/35889533
http://dx.doi.org/10.3390/molecules27144657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315563/
https://www.ncbi.nlm.nih.gov/pubmed/35889533
http://dx.doi.org/10.3390/molecules27144657

Ejemplares similares