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Biotinylated Polymer-Ruthenium Conjugates: In Vitro and In Vivo Studies in a Triple-Negative Breast Cancer Model

The need for new therapeutic approaches for triple-negative breast cancer is a clinically relevant problem that needs to be solved. Using a multi-targeting approach to enhance cancer cell uptake, we synthesized a new family of ruthenium(II) organometallic complexes envisaging simultaneous active and...

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Detalles Bibliográficos
Autores principales: Côrte-Real, Leonor, Brás, Ana Rita, Pilon, Adhan, Mendes, Nuno, Ribeiro, Ana Sofia, Martins, Tiago D., Farinha, José Paulo S., Oliveira, M. Conceição, Gärtner, Fátima, Garcia, M. Helena, Preto, Ana, Valente, Andreia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315599/
https://www.ncbi.nlm.nih.gov/pubmed/35890283
http://dx.doi.org/10.3390/pharmaceutics14071388