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“FLipping” the Story: FLT3-Mutated Acute Myeloid Leukemia and the Evolving Role of FLT3 Inhibitors

SIMPLE SUMMARY: Patients with acute myeloid leukemia (AML) may have a number of different mutations. Those with mutations in the FLT3 gene have a higher risk of relapse and death than those lacking these mutations. FLT3 is a key receptor on the surface of AML cells, which drives cell survival and gr...

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Detalles Bibliográficos
Autores principales: Knight, Tristan E., Edwards, Holly, Meshinchi, Soheil, Taub, Jeffrey W., Ge, Yubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315611/
https://www.ncbi.nlm.nih.gov/pubmed/35884458
http://dx.doi.org/10.3390/cancers14143398