Compritol-Based Nanostrucutured Lipid Carriers (NLCs) for Augmentation of Zolmitriptan Bioavailability via the Transdermal Route: In Vitro Optimization, Ex Vivo Permeation, In Vivo Pharmacokinetic Study

Migraine is a severe neurovascular disease manifested mainly as unilateral throbbing headaches. Triptans are agonists for serotonin receptors. Zolmitriptan (ZMP) is a biopharmaceutics classification system (BCS) class III medication with an absolute oral bioavailability of less than 40%. As a result...

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Detalles Bibliográficos
Autores principales: Hassan, Doaa H., Shohdy, Joseph N., El-Setouhy, Doaa Ahmed, El-Nabarawi, Mohamed, Naguib, Marianne J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315618/
https://www.ncbi.nlm.nih.gov/pubmed/35890379
http://dx.doi.org/10.3390/pharmaceutics14071484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315618/
https://www.ncbi.nlm.nih.gov/pubmed/35890379
http://dx.doi.org/10.3390/pharmaceutics14071484

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