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Identification of New Toxicity Mechanisms in Drug-Induced Liver Injury through Systems Pharmacology

Among adverse drug reactions, drug-induced liver injury presents particular challenges because of its complexity, and the underlying mechanisms are still not completely characterized. Our knowledge of the topic is limited and based on the assumption that a drug acts on one molecular target. We have...

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Detalles Bibliográficos
Autores principales: Moya-García, Aurelio A., González-Jiménez, Andrés, Moreno, Fernando, Stephens, Camilla, Lucena, María Isabel, Ranea, Juan A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315637/
https://www.ncbi.nlm.nih.gov/pubmed/35886075
http://dx.doi.org/10.3390/genes13071292