Upregulated Ca(2+) Release from the Endoplasmic Reticulum Leads to Impaired Presynaptic Function in Familial Alzheimer’s Disease

Neurotransmitter release from presynaptic terminals is primarily regulated by rapid Ca(2+) influx through membrane-resident voltage-gated Ca(2+) channels (VGCCs). Moreover, accumulating evidence indicates that the endoplasmic reticulum (ER) is extensively present in axonal terminals of neurons and p...

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Detalles Bibliográficos
Autores principales: Adeoye, Temitope, Shah, Syed I., Demuro, Angelo, Rabson, David A., Ullah, Ghanim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315668/
https://www.ncbi.nlm.nih.gov/pubmed/35883609
http://dx.doi.org/10.3390/cells11142167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315668/
https://www.ncbi.nlm.nih.gov/pubmed/35883609
http://dx.doi.org/10.3390/cells11142167

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