Development of Self-Emulsifying Drug Delivery Systems (SEDDSs) Displaying Enhanced Permeation of the Intestinal Mucus Following Sustained Release of Prototype Thiol-Based Mucolytic Agent Load

In this study, mucoactive self-emulsifying drug delivery systems (SEDDSs) based on sustained release of N-acetylcysteine (NAC) were developed for providing effective intestinal mucopermeation. Polymeric ionic complexes of NAC were formed with polyethyleneimine (PEI), Eudragit E 100, and Eudragit RS...

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Detalles Bibliográficos
Autores principales: Malkawi, Ahmad, Alrabadi, Nasr, Haddad, Razan, Malkawi, Azhar, Khaled, Khaled, Ovenseri, Airemwen Collins
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315686/
https://www.ncbi.nlm.nih.gov/pubmed/35889482
http://dx.doi.org/10.3390/molecules27144611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315686/
https://www.ncbi.nlm.nih.gov/pubmed/35889482
http://dx.doi.org/10.3390/molecules27144611

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