Real-Time Monitoring of Critical Quality Attributes during High-Shear Wet Granulation Process by Near-Infrared Spectroscopy Effect of Water Addition and Stirring Speed on Pharmaceutical Properties of the Granules

To produce high-quality pharmaceuticals, a real-time monitoring method for the high-shear wet granulation process (HSWG) was developed based on near-infrared spectroscopy (NIRS). Samples consisting of lactose, potato starch, and hydroxypropyl cellulose were prepared using HSWG with varying amounts o...

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Detalles Bibliográficos
Autores principales: Koyanagi, Keita, Ueno, Akinori, Sasaki, Tetsuo, Otsuka, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315720/
https://www.ncbi.nlm.nih.gov/pubmed/35890120
http://dx.doi.org/10.3390/ph15070822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315720/
https://www.ncbi.nlm.nih.gov/pubmed/35890120
http://dx.doi.org/10.3390/ph15070822

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