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Model Re-Estimation: An Alternative for Poor Predictive Performance during External Evaluations? Example of Gentamicin in Critically Ill Patients

Background: An external evaluation is crucial before clinical applications; however, only a few gentamicin population pharmacokinetic (PopPK) models for critically ill patients included it in the model development. In this study, we aimed to evaluate gentamicin PopPK models developed for critically...

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Detalles Bibliográficos
Autores principales: Duong, Alexandre, Simard, Chantale, Williamson, David, Marsot, Amélie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315759/
https://www.ncbi.nlm.nih.gov/pubmed/35890322
http://dx.doi.org/10.3390/pharmaceutics14071426