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Model Re-Estimation: An Alternative for Poor Predictive Performance during External Evaluations? Example of Gentamicin in Critically Ill Patients
Background: An external evaluation is crucial before clinical applications; however, only a few gentamicin population pharmacokinetic (PopPK) models for critically ill patients included it in the model development. In this study, we aimed to evaluate gentamicin PopPK models developed for critically...
Autores principales: | Duong, Alexandre, Simard, Chantale, Williamson, David, Marsot, Amélie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315759/ https://www.ncbi.nlm.nih.gov/pubmed/35890322 http://dx.doi.org/10.3390/pharmaceutics14071426 |
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