In Silico Study of Allosteric Communication Networks in GPCR Signaling Bias

Signaling bias is a promising characteristic of G protein-coupled receptors (GPCRs) as it provides the opportunity to develop more efficacious and safer drugs. This is because biased ligands can avoid the activation of pathways linked to side effects whilst still producing the desired therapeutic ef...

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Detalles Bibliográficos
Autores principales: Morales-Pastor, Adrian, Nerín-Fonz, Francho, Aranda-García, David, Dieguez-Eceolaza, Miguel, Medel-Lacruz, Brian, Torrens-Fontanals, Mariona, Peralta-García, Alejandro, Selent, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315799/
https://www.ncbi.nlm.nih.gov/pubmed/35887157
http://dx.doi.org/10.3390/ijms23147809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315799/
https://www.ncbi.nlm.nih.gov/pubmed/35887157
http://dx.doi.org/10.3390/ijms23147809

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