Cargando…

Synthesis of Quinolones and Zwitterionic Quinolonate Derivatives with Broad-Spectrum Antibiotic Activity

Quinolones are one of the most extensively used therapeutic families of antibiotics. However, the increase in antibiotic-resistant bacteria has rendered many of the available compounds useless. After applying our prediction model of activity against E. coli to a library of 1000 quinolones, two quino...

Descripción completa

Detalles Bibliográficos
Autores principales: Suay-García, Beatriz, Bueso-Bordils, Jose-Ignacio, Antón-Fos, Gerardo, Pérez-Gracia, María-Teresa, Falcó, Antonio, Alemán-López, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315932/
https://www.ncbi.nlm.nih.gov/pubmed/35890116
http://dx.doi.org/10.3390/ph15070818