Increase in Anticancer Drug-Induced Toxicity by Fisetin in Lung Adenocarcinoma A549 Spheroid Cells Mediated by the Reduction of Claudin-2 Expression

Claudin-2 (CLDN2), a component of tight junction, is involved in the reduction of anticancer drug-induced toxicity in spheroids of A549 cells derived from human lung adenocarcinoma. Fisetin, a dietary flavonoid, inhibits cancer cell growth, but its effect on chemosensitivity in spheroids is unknown....

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Detalles Bibliográficos
Autores principales: Eguchi, Hiroaki, Kimura, Riho, Matsunaga, Haruka, Matsunaga, Toshiyuki, Yoshino, Yuta, Endo, Satoshi, Ikari, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316057/
https://www.ncbi.nlm.nih.gov/pubmed/35886884
http://dx.doi.org/10.3390/ijms23147536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316057/
https://www.ncbi.nlm.nih.gov/pubmed/35886884
http://dx.doi.org/10.3390/ijms23147536

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