Another Move towards Bicalutamide Dissolution and Permeability Improvement with Acetylated β-Cyclodextrin Solid Dispersion

The complex formation of antiandrogen bicalutamide (BCL) with methylated (Me-β-CD) and acetylated (Ac-β-CD) β-cyclodextrins was investigated in buffer solution pH 6.8. A two-fold strongly binding of BCL to Ac-β-CD as compared to Me-β-CD was revealed. The solid dispersion of BCL with Ac-β-CD was prep...

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Detalles Bibliográficos
Autores principales: Volkova, Tatyana V., Simonova, Olga R., Perlovich, German L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316079/
https://www.ncbi.nlm.nih.gov/pubmed/35890367
http://dx.doi.org/10.3390/pharmaceutics14071472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316079/
https://www.ncbi.nlm.nih.gov/pubmed/35890367
http://dx.doi.org/10.3390/pharmaceutics14071472

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