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Targeting of p21-Activated Kinase 4 Radiosensitizes Glioblastoma Cells via Impaired DNA Repair

Glioblastoma is a devastating malignant disease with poor patient overall survival. Strong invasiveness and resistance to radiochemotherapy have challenged the identification of molecular targets that can finally improve treatment outcomes. This study evaluates the influence of all six known p21-act...

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Detalles Bibliográficos
Autores principales: Blankenstein, Leon J., Cordes, Nils, Kunz-Schughart, Leoni A., Vehlow, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316146/
https://www.ncbi.nlm.nih.gov/pubmed/35883575
http://dx.doi.org/10.3390/cells11142133