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How a PCR Sequencing Strategy Can Bring New Data to Improve the Diagnosis of Ethionamide Resistance

Ethionamide (ETH) is a second-line antituberculosis drug. ETH resistance (ETH-R) is mainly related to the mutations of the monooxygenase-activating ETH (EthA), the ETH target (InhA), and the inhA promoter. Nonetheless, diagnosing ETH-R is still challenging. We assessed the strategy used for detectin...

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Detalles Bibliográficos
Autores principales: Maitre, Thomas, Morel, Florence, Brossier, Florence, Sougakoff, Wladimir, Jaffre, Jéremy, Cheng, Sokleaph, Veziris, Nicolas, Aubry, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316172/
https://www.ncbi.nlm.nih.gov/pubmed/35889155
http://dx.doi.org/10.3390/microorganisms10071436