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Integrated Transcriptome and Metabolomic Analysis Reveal Anti-Angiogenic Properties of Disarib, a Novel Bcl2-Specific Inhibitor

Transcriptomic profiling of several drugs in cancer cell lines has been utilised to obtain drug-specific signatures and guided combination therapy to combat drug resistance and toxicity. Global metabolomics reflects changes due to altered activity of enzymes, environmental factors, etc. Integrating...

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Detalles Bibliográficos
Autores principales: Manjunath, Meghana, Swaroop, Sai, Pradhan, Sai Sanwid, Rao K, Raksha, Mahadeva, Raghunandan, Sivaramakrishnan, Venketesh, Choudhary, Bibha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316176/
https://www.ncbi.nlm.nih.gov/pubmed/35885991
http://dx.doi.org/10.3390/genes13071208