TNFα-Induced Oxidative Stress and Mitochondrial Dysfunction Alter Hypothalamic Neurogenesis and Promote Appetite Versus Satiety Neuropeptide Expression in Mice

Maternal obesity results in programmed offspring hyperphagia and obesity. The increased offspring food intake is due in part to the preferential differentiation of hypothalamic neuroprogenitor cells (NPCs) to orexigenic (AgRP) vs. anorexigenic (POMC) neurons. The altered neurogenesis may involve hyp...

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Detalles Bibliográficos
Autores principales: Desai, Mina, Stiles, Linsey, Torsoni, Adriana S., Torsoni, Marcio A., Shirihai, Orian S., Ross, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316209/
https://www.ncbi.nlm.nih.gov/pubmed/35884707
http://dx.doi.org/10.3390/brainsci12070900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316209/
https://www.ncbi.nlm.nih.gov/pubmed/35884707
http://dx.doi.org/10.3390/brainsci12070900

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