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The C-Terminal Domain of HIV-1 Integrase: A Swiss Army Knife for the Virus?

Retroviral integrase is a multimeric enzyme that catalyzes the integration of reverse-transcribed viral DNA into the cellular genome. Beyond integration, the Human immunodeficiency virus type 1 (HIV-1) integrase is also involved in many other steps of the viral life cycle, such as reverse transcript...

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Detalles Bibliográficos
Autores principales: Rocchi, Cecilia, Gouet, Patrice, Parissi, Vincent, Fiorini, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316232/
https://www.ncbi.nlm.nih.gov/pubmed/35891378
http://dx.doi.org/10.3390/v14071397