Reducing the Kidney Uptake of High Contrast CXCR4 PET Imaging Agents via Linker Modifications

Purpose: The C-X-C chemokine receptor 4 (CXCR4) is highly expressed in many subtypes of cancers, notably in several kidney-based malignancies. We synthesized, labeled, and assessed a series of radiotracers based on a previous high contrast PET imaging radiopharmaceutical [(68)Ga]Ga-BL02, with modifi...

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Detalles Bibliográficos
Autores principales: Kwon, Daniel, Zhang, Zhengxing, Zeisler, Jutta, Kuo, Hsiou-Ting, Lin, Kuo-Shyan, Benard, Francois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316317/
https://www.ncbi.nlm.nih.gov/pubmed/35890397
http://dx.doi.org/10.3390/pharmaceutics14071502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316317/
https://www.ncbi.nlm.nih.gov/pubmed/35890397
http://dx.doi.org/10.3390/pharmaceutics14071502

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