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Design, Synthesis and Molecular Docking of Novel Acetophenone-1,2,3-Triazoles Containing Compounds as Potent Enoyl-Acyl Carrier Protein Reductase (InhA) Inhibitors

New medications are desperately needed to combat rising drug resistance among tuberculosis (TB) patients. New agents should ideally work through unique targets to avoid being hampered by preexisting clinical resistance to existing treatments. The enoyl-acyl carrier protein reductase InhA of M. tuber...

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Detalles Bibliográficos
Autores principales: Albelwi, Fawzia Faleh, Abdu Mansour, Hanaa M., Elshatanofy, Maram M., El Kilany, Yeldez, Kandeel, Kamal, Elwakil, Bassma H., Hagar, Mohamed, Aouad, Mohamed Reda, El Ashry, El Sayed H., Rezki, Nadjet, El Sawy, Maged A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316523/
https://www.ncbi.nlm.nih.gov/pubmed/35890098
http://dx.doi.org/10.3390/ph15070799