Mechanism Study on Nanoparticle Negative Surface Charge Modification by Ascorbyl Palmitate and Its Improvement of Tumor Targeting Ability

Surface charge polarity and density influence the immune clearance and cellular uptake of intravenously administered lipid nanoparticles (LNPs), thus determining the efficiency of their delivery to the target. Here, we modified the surface charge with ascorbyl palmitate (AsP) used as a negatively ch...

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Detalles Bibliográficos
Autores principales: Li, Lin, Wang, Hongliang, Ye, Jun, Chen, Yankun, Wang, Renyun, Jin, Dujia, Liu, Yuling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316582/
https://www.ncbi.nlm.nih.gov/pubmed/35889281
http://dx.doi.org/10.3390/molecules27144408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316582/
https://www.ncbi.nlm.nih.gov/pubmed/35889281
http://dx.doi.org/10.3390/molecules27144408

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