Cargando…

Mechanism Study on Nanoparticle Negative Surface Charge Modification by Ascorbyl Palmitate and Its Improvement of Tumor Targeting Ability

Surface charge polarity and density influence the immune clearance and cellular uptake of intravenously administered lipid nanoparticles (LNPs), thus determining the efficiency of their delivery to the target. Here, we modified the surface charge with ascorbyl palmitate (AsP) used as a negatively ch...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Lin, Wang, Hongliang, Ye, Jun, Chen, Yankun, Wang, Renyun, Jin, Dujia, Liu, Yuling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316582/ https://www.ncbi.nlm.nih.gov/pubmed/35889281 http://dx.doi.org/10.3390/molecules27144408

Ejemplares similares

Ascorbyl palmitate-incorporated paclitaxel-loaded composite nanoparticles for synergistic anti-tumoral therapy
por: Zhou, Min, et al.
Publicado: (2017)

Synthesis and In Vitro Characterization of Ascorbyl Palmitate-Loaded Solid Lipid Nanoparticles
por: Ledinski, Maja, et al.
Publicado: (2022)

Ascorbyl Palmitate Hydrogel for Local, Intestinal Delivery of Macromolecules
por: Zhai, Jinyi, et al.
Publicado: (2018)

Synthesis with Immobilized Lipases and Downstream Processing of Ascorbyl Palmitate
por: Tufiño, Carolina, et al.
Publicado: (2019)

Preparation of magnetic nanoparticle integrated nanostructured lipid carriers for controlled delivery of ascorbyl palmitate
por: Kalaycioglu, Gokce Dicle
Publicado: (2020)

Cytotoxicity and Genotoxicity Assessment of Ascorbyl Palmitate (AP) Food Additive
por: Sohrabi, Yousef, et al.
Publicado: (2018)

Enzymatic Synthesis of Ascorbyl Palmitate in a Rotating Bed Reactor
por: Holtheuer, Jessica, et al.
Publicado: (2023)

Usefulness of Urea as a Means of Improving the Solubility of Poorly Water-Soluble Ascorbyl Palmitate
por: Inoue, Yutaka, et al.
Publicado: (2017)

Sublingual Delivery of Astaxanthin through a Novel Ascorbyl Palmitate-Based Nanoemulsion: Preliminary Data
por: Fratter, Andrea, et al.
Publicado: (2019)

Spectroscopic, thermodynamic and molecular docking studies of bovine serum albumin interaction with ascorbyl palmitate food additive
por: Sohrabi, Yousef, et al.
Publicado: (2017)

A New Treatment for Local Adiposity with Ascorbic Acid and Ascorbyl-Palmitate Solution: Clinical and Histological Study
por: Scarano, Antonio, et al.
Publicado: (2020)

The Inhibitory Effects of Hydroxytyrosol, α-Tocopherol and Ascorbyl Palmitate on Lipid Peroxidation in Deep-Fat Fried Seafood
por: Theah, Audrey Yue Vern, et al.
Publicado: (2023)

Improved Safety and Anti-Glioblastoma Efficacy of CAT3-Encapsulated SMEDDS through Metabolism Modification
por: Wang, Hongliang, et al.
Publicado: (2021)

Lipomatrix: A Novel Ascorbyl Palmitate-Based Lipid Matrix to Enhancing Enteric Absorption of Serenoa Repens Oil
por: Fratter, Andrea, et al.
Publicado: (2019)

Ascorbyl palmitate synthesis in an organic solvent system using a Celite-immobilized commercial lipase (Lipolase 100L)
por: Sharma, Shivika, et al.
Publicado: (2016)

Towards Celiac-safe foods: Decreasing the affinity of transglutaminase 2 for gliadin by addition of ascorbyl palmitate and ZnCl(2) as detoxifiers
por: Engstrom, N., et al.
Publicado: (2017)

Topical Application of Trisodium Ascorbyl 6-Palmitate 2-Phosphate Actively Supplies Ascorbate to Skin Cells in an Ascorbate Transporter-Independent Manner
por: Shibuya, Shuichi, et al.
Publicado: (2017)

Synthesis of L-Ascorbyl Flurbiprofenate by Lipase-Catalyzed Esterification and Transesterification Reactions
por: Xin, Jia-ying, et al.
Publicado: (2017)

Mechanisms of Ascorbyl Radical Formation in Human Platelet-Rich Plasma
por: Shyu, Kou-Gi, et al.
Publicado: (2014)

Ascorbyl palmitate/d-α-tocopheryl polyethylene glycol 1000 succinate monoester mixed micelles for prolonged circulation and targeted delivery of compound K for antilung cancer therapy in vitro and in vivo
por: Zhang, Youwen, et al.
Publicado: (2017)

Efficacy and safety of disodium ascorbyl phytostanol phosphates in men with moderate dyslipidemia
por: Vissers, Maud N., et al.
Publicado: (2008)

Magnesium Ascorbyl Phosphate Regulates the Expression of Inflammatory Biomarkers in Cultured Sebocytes
por: Lee, Weon Ju, et al.
Publicado: (2015)

Controlling deposition of nanoparticles by tuning surface charge of SiO(2) by surface modifications
por: Eklöf, Johnas, et al.
Publicado: (2016)

Glycation of bovine serum albumin by ascorbate in vitro: Possible contribution of the ascorbyl radical?
por: Sadowska-Bartosz, Izabela, et al.
Publicado: (2015)

Ascorbylation of a Reactive Cysteine in the Major Apple Allergen Mal d 1
por: Ahammer, Linda, et al.
Publicado: (2022)

Surface Modification and Charge Injection in a Nanocomposite Of Metal Nanoparticles and Semiconductor Oxide Nanostructures
por: Xiao, Bo, et al.
Publicado: (2020)

Simultaneous Analysis of Hydroquinone, Arbutin, and Ascorbyl Glucoside Using a Nanocomposite of Ag@AgCl Nanoparticles, Ag(2)S Nanoparticles, Multiwall Carbon Nanotubes, and Chitosan
por: Butwong, Nutthaya, et al.
Publicado: (2020)

Cellular uptake mechanism and comparative evaluation of antineoplastic effects of paclitaxel–cholesterol lipid emulsion on triple-negative and non-triple-negative breast cancer cell lines
por: Ye, Jun, et al.
Publicado: (2016)

The Anti-Arthritic Efficacy of Khellin Loaded in Ascorbyl Decanoate Nanovesicles after an Intra-Articular Administration
por: Vanti, Giulia, et al.
Publicado: (2021)

Improving the Oral Bioavailability of an Anti-Glioma Prodrug CAT3 Using Novel Solid Lipid Nanoparticles Containing Oleic Acid-CAT3 Conjugates
por: Wang, Hongliang, et al.
Publicado: (2020)

Precise modification of the surface charge of antigen enhances vaccine immunogenicity
por: Zai, Xiaodong, et al.
Publicado: (2023)

Electron spin resonance study of changes during development of solid Yoshida tumour. I: Ascorbyl radical.
por: Silcock, J. M., et al.
Publicado: (1976)

Dynamic nuclear polarization-magnetic resonance imaging at low ESR irradiation frequency for ascorbyl free radicals
por: Ito, Shinji, et al.
Publicado: (2016)

Opinion on the re‐evaluation of ascorbyl palmitate (E 304i) as a food additive in foods for infants below 16 weeks of age and the follow‐up of its re‐evaluation as a food additive for uses in foods for all population groups
por: Younes, Maged, et al.
Publicado: (2020)

Publisher Correction: Surface Modification and Charge Injection in a Nanocomposite Of Metal Nanoparticles and Semiconductor Oxide Nanostructures
por: Xiao, Bo, et al.
Publicado: (2020)

Preparation and evaluation of ofloxacin-loaded palmitic acid solid lipid nanoparticles
por: Xie, Shuyu, et al.
Publicado: (2011)

Electron spin resonance study of changes during the development of a mouse myeloid leukaemia. II. The ascorbyl radical.
por: Dodd, N. J., et al.
Publicado: (1975)

Nanoparticles with High-Surface Negative-Charge Density Disturb the Metabolism of Low-Density Lipoprotein in Cells
por: Bai, Xue, et al.
Publicado: (2018)

Synthesis of Positively and Negatively Charged CeO(2) Nanoparticles: Investigation of the Role of Surface Charge on Growth and Development of Drosophila melanogaster
por: Parimi, Divya, et al.
Publicado: (2019)

Modification of textile surfaces using nanoparticles
por: Vigneshwaran, N.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_t5v1pne8kskf2bgspjfb3k17nj