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Molecular and Nano-Structural Optimization of Nanoparticulate Mn(2+)-Hexarhenium Cluster Complexes for Optimal Balance of High T(1)- and T(2)-Weighted Contrast Ability with Low Hemoagglutination and Cytotoxicity

The present work introduces rational design of nanoparticulate Mn(II)-based contrast agents through both variation of the μ(3) (inner) ligands within a series of hexarhenium cluster complexes [{Re(6)(μ(3)-Q)(8)}(CN)(6)](4)(−) (Re(6)Q(8), Q = S(2−), Se(2−) or Te(2−)) and interfacial decoration of the...

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Detalles Bibliográficos
Autores principales: Akhmadeev, Bulat Salavatovich, Nizameev, Irek R., Kholin, Kirill V., Voloshina, Alexandra D., Gerasimova, Tatyana P., Gubaidullin, Aidar T., Kadirov, Marsil K., Ismaev, Ildus E., Brylev, Konstantin A., Zairov, Rustem R., Mustafina, Asiya R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316779/
https://www.ncbi.nlm.nih.gov/pubmed/35890403
http://dx.doi.org/10.3390/pharmaceutics14071508