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Molecular and Nano-Structural Optimization of Nanoparticulate Mn(2+)-Hexarhenium Cluster Complexes for Optimal Balance of High T(1)- and T(2)-Weighted Contrast Ability with Low Hemoagglutination and Cytotoxicity
The present work introduces rational design of nanoparticulate Mn(II)-based contrast agents through both variation of the μ(3) (inner) ligands within a series of hexarhenium cluster complexes [{Re(6)(μ(3)-Q)(8)}(CN)(6)](4)(−) (Re(6)Q(8), Q = S(2−), Se(2−) or Te(2−)) and interfacial decoration of the...
Autores principales: | Akhmadeev, Bulat Salavatovich, Nizameev, Irek R., Kholin, Kirill V., Voloshina, Alexandra D., Gerasimova, Tatyana P., Gubaidullin, Aidar T., Kadirov, Marsil K., Ismaev, Ildus E., Brylev, Konstantin A., Zairov, Rustem R., Mustafina, Asiya R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316779/ https://www.ncbi.nlm.nih.gov/pubmed/35890403 http://dx.doi.org/10.3390/pharmaceutics14071508 |
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