Synthesis and Systematic Study on the Effect of Different PEG Units on Stability of PEGylated, Integrin-αvβ6-Specific A20FMDV2 Analogues in Rat Serum and Human Plasma

A20FMDV2 is a 20-mer peptide that exhibits high selectivity and affinity for the tumour-related αvβ6 integrin that can compete with extracellular ligands for the crucial RGD binding site, playing a role as a promising αvβ6-specific inhibitor for anti-cancer therapies. Unfortunately, the clinical val...

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Detalles Bibliográficos
Autores principales: Hung, Kuo-yuan, Kowalczyk, Renata, Desai, Ami, Brimble, Margaret A., Marshall, John F., Harris, Paul W. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316855/
https://www.ncbi.nlm.nih.gov/pubmed/35889207
http://dx.doi.org/10.3390/molecules27144331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316855/
https://www.ncbi.nlm.nih.gov/pubmed/35889207
http://dx.doi.org/10.3390/molecules27144331

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