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Translating a Thin-Film Rehydration Method to Microfluidics for the Preparation of a SARS-CoV-2 DNA Vaccine: When Manufacturing Method Matters

Previous investigations conducted on a liposomal formulation for a SARS-CoV-2 DNA vaccine manufactured using the thin-film layer rehydration method showed promising immunogenicity results in mice. The adaptation of the liposomal formulation to a scalable and reproducible method of manufacture is nec...

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Detalles Bibliográficos
Autores principales: Peletta, Allegra, Prompetchara, Eakachai, Tharakhet, Kittipan, Kaewpang, Papatsara, Buranapraditkun, Supranee, Yostrerat, Nongnaphat, Manopwisedjaroen, Suwimon, Thitithanyanont, Arunee, Avaro, Jonathan, Krupnik, Leonard, Neels, Antonia, Ruxrungtham, Kiat, Ketloy, Chutitorn, Borchard, Gerrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316859/
https://www.ncbi.nlm.nih.gov/pubmed/35890321
http://dx.doi.org/10.3390/pharmaceutics14071427