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Modeling an Optimal 3D Skin-on-Chip within Microfluidic Devices for Pharmacological Studies

Preclinical research remains hampered by an inadequate representation of human tissue environments which results in inaccurate predictions of a drug candidate’s effects and target’s suitability. While human 2D and 3D cell cultures and organoids have been extensively improved to mimic the precise str...

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Detalles Bibliográficos
Autores principales: Fernandez-Carro, Estibaliz, Angenent, Maricke, Gracia-Cazaña, Tamara, Gilaberte, Yolanda, Alcaine, Clara, Ciriza, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316928/
https://www.ncbi.nlm.nih.gov/pubmed/35890312
http://dx.doi.org/10.3390/pharmaceutics14071417