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Integrating knowledge and omics to decipher mechanisms via large‐scale models of signaling networks

Signal transduction governs cellular behavior, and its dysregulation often leads to human disease. To understand this process, we can use network models based on prior knowledge, where nodes represent biomolecules, usually proteins, and edges indicate interactions between them. Several computational...

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Detalles Bibliográficos
Autores principales: Garrido‐Rodriguez, Martin, Zirngibl, Katharina, Ivanova, Olga, Lobentanzer, Sebastian, Saez‐Rodriguez, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316933/
https://www.ncbi.nlm.nih.gov/pubmed/35880747
http://dx.doi.org/10.15252/msb.202211036