Intranasal Delivery of Granisetron to the Brain via Nanostructured Cubosomes-Based In Situ Gel for Improved Management of Chemotherapy-Induced Emesis

This research aimed to boost granisetron (GS) delivery to the brain via the intranasal route to better manage chemotherapy-induced emesis. Glycerol monooleate (GMO), Poloxamer 407 (P 407) and Tween 80 (T 80) were used to formulate GS-loaded cubosomes (GS-CBS) utilizing a melt dispersion-emulsificati...

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Detalles Bibliográficos
Autores principales: Eissa, Essam M., Elkomy, Mohammed H., Eid, Hussein M., Ali, Adel A., Abourehab, Mohammed A. S., Alsubaiyel, Amal M., Naguib, Ibrahim A., Alsalahat, Izzeddin, Hassan, Amira H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316995/
https://www.ncbi.nlm.nih.gov/pubmed/35890270
http://dx.doi.org/10.3390/pharmaceutics14071374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316995/
https://www.ncbi.nlm.nih.gov/pubmed/35890270
http://dx.doi.org/10.3390/pharmaceutics14071374

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