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Intranasal Delivery of Granisetron to the Brain via Nanostructured Cubosomes-Based In Situ Gel for Improved Management of Chemotherapy-Induced Emesis

This research aimed to boost granisetron (GS) delivery to the brain via the intranasal route to better manage chemotherapy-induced emesis. Glycerol monooleate (GMO), Poloxamer 407 (P 407) and Tween 80 (T 80) were used to formulate GS-loaded cubosomes (GS-CBS) utilizing a melt dispersion-emulsificati...

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Detalles Bibliográficos
Autores principales:	Eissa, Essam M., Elkomy, Mohammed H., Eid, Hussein M., Ali, Adel A., Abourehab, Mohammed A. S., Alsubaiyel, Amal M., Naguib, Ibrahim A., Alsalahat, Izzeddin, Hassan, Amira H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9316995/ https://www.ncbi.nlm.nih.gov/pubmed/35890270 http://dx.doi.org/10.3390/pharmaceutics14071374

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