PEG-Free Polyion Complex Nanocarriers for Brain-Derived Neurotrophic Factor

Many therapeutic formulations incorporate poly(ethylene glycol) (PEG) as a stealth component to minimize early clearance. However, PEG is immunogenic and susceptible to accelerated clearance after multiple administrations. Here, we present two novel reformulations of a polyion complex (PIC), origina...

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Detalles Bibliográficos
Autores principales: Fay, James M., Lim, Chaemin, Finkelstein, Anna, Batrakova, Elena V., Kabanov, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317007/
https://www.ncbi.nlm.nih.gov/pubmed/35890287
http://dx.doi.org/10.3390/pharmaceutics14071391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317007/
https://www.ncbi.nlm.nih.gov/pubmed/35890287
http://dx.doi.org/10.3390/pharmaceutics14071391

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