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A New Alternative Tool to Analyse Glycosylation in Monoclonal Antibodies Based on Drop-Coating Deposition Raman imaging: A Proof of Concept

Glycosylation is considered a critical quality attribute of therapeutic proteins as it affects their stability, bioactivity, and safety. Hence, the development of analytical methods able to characterize the composition and structure of glycoproteins is crucial. Existing methods are time consuming, e...

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Detalles Bibliográficos
Autores principales: Hamla, Sabrina, Sacré, Pierre-Yves, Derenne, Allison, Cowper, Ben, Goormaghtigh, Erik, Hubert, Philippe, Ziemons, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317070/
https://www.ncbi.nlm.nih.gov/pubmed/35889277
http://dx.doi.org/10.3390/molecules27144405