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A New Alternative Tool to Analyse Glycosylation in Monoclonal Antibodies Based on Drop-Coating Deposition Raman imaging: A Proof of Concept
Glycosylation is considered a critical quality attribute of therapeutic proteins as it affects their stability, bioactivity, and safety. Hence, the development of analytical methods able to characterize the composition and structure of glycoproteins is crucial. Existing methods are time consuming, e...
Autores principales: | Hamla, Sabrina, Sacré, Pierre-Yves, Derenne, Allison, Cowper, Ben, Goormaghtigh, Erik, Hubert, Philippe, Ziemons, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317070/ https://www.ncbi.nlm.nih.gov/pubmed/35889277 http://dx.doi.org/10.3390/molecules27144405 |
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