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Medicinal Hypervalent Tellurium Prodrugs Bearing Different Ligands: A Comparative Study of the Chemical Profiles of AS101 and Its Halido Replaced Analogues

Ammonium trichloro (dioxoethylene-O,O′) tellurate (AS101) is a potent immunomodulator prodrug that, in recent years, entered various clinical trials and was tested for a variety of potential therapeutic applications. It has been demonstrated that AS101 quickly activates in aqueous milieu, producing...

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Detalles Bibliográficos
Autores principales: Chiaverini, Lorenzo, Cirri, Damiano, Tolbatov, Iogann, Corsi, Francesca, Piano, Ilaria, Marrone, Alessandro, Pratesi, Alessandro, Marzo, Tiziano, La Mendola, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317073/
https://www.ncbi.nlm.nih.gov/pubmed/35886853
http://dx.doi.org/10.3390/ijms23147505