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Co-Delivery of Repurposing Itraconazole and VEGF siRNA by Composite Nanoparticulate System for Collaborative Anti-Angiogenesis and Anti-Tumor Efficacy against Breast Cancer

Combinations of two different therapeutic modalities of VEGF inhibitors against angiogenesis can cooperatively impede breast cancer tumor growth and enhance therapeutic efficacy. Itraconazole (ITZ) is a conventional antifungal drug with high safety; however, it has been repurposed to be a multi targ...

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Detalles Bibliográficos
Autores principales: Jin, Mingji, Zeng, Bowen, Liu, Yanhong, Jin, Lili, Hou, Yan, Liu, Chao, Liu, Wei, Wu, Hao, Chen, Liqing, Gao, Zhonggao, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317122/
https://www.ncbi.nlm.nih.gov/pubmed/35890264
http://dx.doi.org/10.3390/pharmaceutics14071369