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Analyzing and Resolving Infeasibility in Flux Balance Analysis of Metabolic Networks

Flux balance analysis (FBA) is a key method for the constraint-based analysis of metabolic networks. A technical problem may occur in FBA when known (e.g., measured) fluxes of certain reactions are integrated into an FBA scenario rendering the underlying linear program (LP) infeasible, for example,...

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Detalles Bibliográficos
Autores principales: Klamt, Steffen, von Kamp, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317134/
https://www.ncbi.nlm.nih.gov/pubmed/35888712
http://dx.doi.org/10.3390/metabo12070585