Potent CCR3 Receptor Antagonist, SB328437, Suppresses Colonic Eosinophil Chemotaxis and Inflammation in the Winnie Murine Model of Spontaneous Chronic Colitis

Eosinophils and their regulatory molecules have been associated with chronic intestinal inflammation and gastrointestinal dysfunctions; eosinophil accumulation in the gut is prominent in inflammatory bowel disease (IBD). The chemokine receptor CCR3 plays a pivotal role in local and systemic recruitm...

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Detalles Bibliográficos
Autores principales: Filippone, Rhiannon T., Dargahi, Narges, Eri, Rajaraman, Uranga, Jose A., Bornstein, Joel C., Apostolopoulos, Vasso, Nurgali, Kulmira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317166/
https://www.ncbi.nlm.nih.gov/pubmed/35887133
http://dx.doi.org/10.3390/ijms23147780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9317166/
https://www.ncbi.nlm.nih.gov/pubmed/35887133
http://dx.doi.org/10.3390/ijms23147780

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